Nicotine, a compound mostly based in the plants of the Solanaceae family, is an alkaloid which is found accumulated within the leaves of these plants, although biosynthesis of the chemical happens in the roots of the plants. Nicotine is amongst the major the different parts of addictive plants like tobacco (0.6%-3.0%) which is the real reason for their addiction in humans due to its psychoactive nature.
The follow are 10 interesting facts about viibryd side effects.
1. Etymology
The name nicotine comes from the scientific name of the tobacco plant Nicotiana tabacum. The scientific name of the tobacco plant is itself named france ambassador to Portugal Jean Nicot de Villemain. Villeman is credited for sending tobacco seeds and plant saplings to Paris in 1560 for its use within medicinal purposes.
2. Extraction
Nicotine was basically purchased from the tobacco plant by German physician Dr. Wilhelm Heinrich Posselt and chemist Karl Ludwig Reimann in 1828. After its discovery Posselt and Reimann labelled becoming a poison. In reality nicotine is an antiherbivore chemical, which then causes addiction when consumed in a small amount (1mg or fewer) and death if consumed high amounts (30mg-60mg).
3. Chemistry
Nicotine is an alkaloid using the chemical formula C10H14N2. Its IUPAC name is 3[2,5-1-methylpyrrolidin-2-yl]pyridine. It has a molecular mass of 162.12g/mol. Nicotine is a hygroscopic liquid which is miscible with water as a nitrogenous base. Its density is 1.01g/cm3, melting point -79oC and boiling point 247oC. The nicotine molecule has a half time of Couple of hours and its metabolism is hepatic. Nicotine is also optically active and has two enantiomeric forms.
4. Nicotine being an insecticide
As already said nicotine is an antiherbivore drug which if consumed a lot is fatal to life forms. That’s the reason nicotine laden tobacco has been employed being an insecticide before the planet War II. But as soon as the WWII its usage drastically lowered because of the availability of cheap synthetic insecticides which are more easily available than tobacco much less harmful to mammals. In the current times the hype surrounding organic farming has again increased the interest of the farmers within the use of tobacco as a pesticide being an alternate to traps.
5. Nicotine addiction
Our nerves inside the body has certain nicotinic acetylcholine receptors. Nicotine binds to a few of these and boosts the amount of several neurotransmitters. Among these neurotransmitters dopamine is but one such neurotransmitter which is significantly increased during nicotine use which is accountable for the sense of euphoria and relaxation brought on by the use of tobacco (nicotine) products.
6. Psychoactive effects of nicotine
Nicotine is a psychoactive substance because it is mood altering. It causes both euphoria and relaxation. By the body processes nicotine is metabolised within the liver. First after its metabolism nicotine ends in the release of glucose from the liver and epinephrine from the adrenal medulla. This sudden relieve glucose and epinephrine causes euphoria as soon as the use of nicotine. Following your initial euphoria nicotine contributes to relaxation, increased alertness and sharpness by taking care of different neurotransmitters of the body. Nicotine boasts pain relieving properties.
7. Unwanted side effects of nicotine intake
Tough it appears as though nicotine is an excellent substance to boost one’s sharpness, induce calmness and elevate one’s mood there are far more negative facets of nicotine intake than positive. Among these the commonest negative effects of nicotine intake are a greater probability of hypertension and cardiac arrest. It really is sad that each cigarette that the man smokes reduces his lifespan by 14 years. Moreover since nicotine has been seen as to affect the working of Estrogen on hippocampus, hence in the end nicotine users are susceptible to amnesia and other associated diseases.
8. Toxicity
Nicotine is considered to be more toxic than most frequent drugs like heroin and cocaine. More harm is conducted by nicotine to the body which is readily absorbed by the bloodstream and reaches mental performance from the lungs within 7 seconds of the intake either orally or as the nicotine patch.
9. Use of nicotine in medical science
Though nicotine is very little doctor’s best ally, it can be yet not his worst foe. Nicotine noted for its pain relieving properties has researched upon to be used as a potential pain killer minus its harmful effects. Nicotine has additionally been found to lessen preeclampsia, allergic asthma; and the like by serving as an anti-inflammatory agent.
10. Nicotine in literature
Nicotine may be personified in popular literature as Nick O’ Teen, a humanoid villainous character in Superman comics that has been created as a part of anti-nicotine drive to educate children in regards to the ill-effects of nicotine intake in any form.
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