SINCE The second world war, medical science has progressed into a stage where competitive medications are around for treat the same ailment in different people. It’s not nearly brands (the industry trade issue) but generic drugs (the industry scientific issue). In this report, we shall consider the various factors that decide picking a a specific drug.
Safety: These sub-criteria has to be considered underneath the criterion of safety:
* Acute therapeutic index: In the event the patient’s condition is acute, how effective is really a particular drug even though it’s got certain side-effects so long as the acuteness of the condition is lowered? Example: narcotic pain-killers work well in healing pain but feature the possible side-effect of addiction.
* Long-term safety: http://medicationdirectory.com could be safe in short-term treatment, but how safe it really is in long-term treatment? Example: antibiotics are acceptable in short-term treatment, but tend to have undesirable effects in the case of prolonged use.
* Drug-drug interaction risk: Drugs are chemicals, and lots of chemicals respond to develop a different chemical, that have an effect that may harm the person or aggravate his/her condition. Example: A tricyclic anti-depressant and alcohol interact to create a new condition that warrants separate treatment.
Drug-drug interaction risk is of 2 types:
· Pharmacokinetic: In this type of drug-drug interaction, two drugs, outside of one another, have certain effects using one or even more body processes (e.g., metabolism) that affects the performance of the other. Example: Darvocet-N (propoxyphene and acetaminophen) inhibits the action of a liver enzyme that Lexapro (escitalopram) depends on for the metabolism. This will cause a boost in the side-effects of Lexapro.
· Pharmacodynamic: Here, several drugs actually generate the same relation to the same organ, thus enhancing the total, added effect. Example: Lexapro has certain side-effects for example drowsiness and fatigue. Darvocet-N also acts similarly around the brain. Thus, the side-effects of the two medicine is more intense.
Tolerability: A drug could be effective and not tolerable by all patients. Example: Allergies to a particular drugs in certain people. Short-term and long-term tolerability should be taken into consideration. Efficacy: A drug is not equally great at all patients. For instance, some patients with depression or anxiety attacks experience reduced escitalopram, but there are lots of that do not, who therefore should be prescribed some other anti-depressant. The rate of onset of therapeutic action is an important factor to be considered too.
Cost: Cost does not necessarily mean the price tag on acquisition of some medicine alone. It must also cover the price tag on treatment of a complication that may arise from using some other drug. Example: In a individual who insists on taking alcohol nevertheless should be treated for depression is normally administered an SSRI drug because they drugs don’t potentiate the end results of alcohol, whereas another gang of anti-depressants (for example tricyclics) could cause a whole new symptom in such patients, which may need a different and expensive treatment. Therefore, it’s easier to prescribe the more expensive escitalopram as opposed to a cheaper tricyclic in this patients.
Simplicity of treatment: The simplest mode of administration is preferred. If you find an alternative between a shot and oral administration, the latter is preferred if the efficacy of the two modes can be compared. Or, local application is chosen over the oral route where possible; e.g., antibiotic treatment of eye infections. Dosage and frequency of administration too are a key factor to decide simple treatment.
More info about http://medicationdirectory.com go to see this net page: click for info