SINCE World war 2, medical science has progressed with a stage where competitive medications are around for treat exactly the same ailment in several people. This isn’t just about brands (that is a trade issue) but generic drugs (that is a scientific issue). Within this report, we shall glance at the various factors that decide selecting a certain drug.
Safety: The next sub-criteria should be considered beneath the criterion of safety:
* Acute therapeutic index: If the patient’s condition is acute, how effective is often a particular drug regardless of whether it’s certain side-effects as long as the acuteness in the condition is lowered? Example: narcotic pain-killers work well in healing pain but include the potential side-effect of addiction.
* Long-term safety: medicationdirectory.com could be safe in short-term treatment, but how safe it really is in long-term treatment? Example: antibiotics are acceptable in short-term treatment, but tend to have undesirable effects in the event of prolonged use.
* Drug-drug interaction risk: Medicine is chemicals, and several chemicals react to develop a different chemical, which has an effect which could harm the individual or aggravate his/her condition. Example: A tricyclic anti-depressant and alcohol interact to produce a new condition that warrants separate treatment.
Drug-drug interaction risk is of two types:
· Pharmacokinetic: In this kind of drug-drug interaction, two drugs, independent of one another, have certain effects one or maybe more body processes (e.g., metabolism) that affects the performance in the other. Example: Darvocet-N (propoxyphene and acetaminophen) inhibits the act of a liver enzyme that Lexapro (escitalopram) is dependent upon for the metabolism. This leads to an increase in the side-effects of Lexapro.
· Pharmacodynamic: Here, several drugs actually produce the same relation to exactly the same organ, thus enhancing the total, added effect. Example: Lexapro has certain side-effects such as drowsiness and fatigue. Darvocet-N also acts similarly around the brain. Thus, the side-effects of both medicine is more intense.
Tolerability: A medicine could be effective although not tolerable by all patients. Example: Allergies to particular drugs in a few people. Short-term and long-term tolerability have to be taken into consideration. Efficacy: A medicine is not equally effective in all patients. For example, some patients with depression or panic disorders experience rest from escitalopram, but there are lots of that do not, who therefore have to be prescribed some other anti-depressant. The speed of oncoming of therapeutic action is a crucial factor to be regarded as too.
Cost: Cost does not necessarily mean the expense of acquiring a certain medicine alone. It ought to also cover the expense of treating a complication which could arise by using some other drug. Example: Inside a one who insists on taking alcohol but should be treated for depression is normally administered an SSRI drug as these drugs don’t potentiate the results of alcohol, whereas another gang of anti-depressants (such as tricyclics) may cause a whole new condition in such patients, which will require a various and expensive treatment. Therefore, it’s safer to prescribe the more costly escitalopram rather than a cheaper tricyclic in such patients.
Simplicity of treatment: The best mode of administration is preferred. If you find an option between a shot and oral administration, aforementioned is preferred in the event the efficacy of both modes can be compared. Or, local application is chosen over the oral route where possible; e.g., antibiotic treating eye infections. Dosage and frequency of administration too are a key factor to make a decision simple treatment.
For more info about medicationdirectory.com you can check this popular net page: web link